344212BR
Nov 03, 2022
USA
Job Description
253M people worldwide are visually impaired of which 80% can be prevented or cured. Novartis is reimagining the treatment and prevention of visual impairment and blindness. We aim to develop life-changing pharmaceuticals and transformative technologies for diseases and conditions from front to back of the eye. NIBR’s Ophthalmology group is working on treatments for the leading causes of blindness as well as cell and gene therapies for rare diseases, a new frontier in medicine that can enable us to transform eye care for patient.
The Translational Medicine (TM ) Discovery & Profiling (TMDP) group is a team of physicians and clinical researchers who drive that innovation science from discovery to the patient through the selection, profiling and effective development of medicines.
In the role of Ophthalmology (OPHTHA) TM Expert you will develop high value decision-strategies for the Translational Medicine component of drug development projects through the PoC phase.
Your main accountabilities will include but not be limited to:
• Lead global project teams to develop clinical strategy and drive implementation of clinical development plan, providing medical and scientific leadership and oversight; participate in project teams through program life cycle from New Target Review Committee (NTRC) stage to registration. • Be responsible for clinical portions of the Integrated Development Plan (IDP) • Implement studies from First-in-man to Proof of concept phase . This may include methodology studies to identify and validate novel endpoints for early decision making in PoC studies.
• Present clinical strategy to to relevant Decision Boards (e.g. DADB, TED).
• Work closely with Biomarker Expert to develop and implement compound related biomarker strategies in implementation.
• Collaborate with research scientists to identify, develop, and implement strategy for preclinical support of program-related objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities.
• Contribute to Health authority interactions and documents as TM Expert
This position will be located at the Cambridge, MA or the Basel, Switzerland site and will not have the ability to be located remotely. This position will require up to 25% travel as defined by the business (domestic and/ or international).
The Translational Medicine (TM ) Discovery & Profiling (TMDP) group is a team of physicians and clinical researchers who drive that innovation science from discovery to the patient through the selection, profiling and effective development of medicines.
In the role of Ophthalmology (OPHTHA) TM Expert you will develop high value decision-strategies for the Translational Medicine component of drug development projects through the PoC phase.
Your main accountabilities will include but not be limited to:
• Lead global project teams to develop clinical strategy and drive implementation of clinical development plan, providing medical and scientific leadership and oversight; participate in project teams through program life cycle from New Target Review Committee (NTRC) stage to registration. • Be responsible for clinical portions of the Integrated Development Plan (IDP) • Implement studies from First-in-man to Proof of concept phase . This may include methodology studies to identify and validate novel endpoints for early decision making in PoC studies.
• Present clinical strategy to to relevant Decision Boards (e.g. DADB, TED).
• Work closely with Biomarker Expert to develop and implement compound related biomarker strategies in implementation.
• Collaborate with research scientists to identify, develop, and implement strategy for preclinical support of program-related objectives. This includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications, and other relevant activities.
• Contribute to Health authority interactions and documents as TM Expert
This position will be located at the Cambridge, MA or the Basel, Switzerland site and will not have the ability to be located remotely. This position will require up to 25% travel as defined by the business (domestic and/ or international).
Diversity & Inclusion / EEO
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Minimum Requirements
Minimum requirements :
What you bring to the role:
Doctoral degree, MD strongly preferred - 5 plus years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience - Significant contributions to a field over time, creates new concepts - Recognized publications record - Excellent written and oral communication/presentation skills - Independence: Able to work independently on study planning and execution, and with supervision on project planning, - Innovation: Seeks out new clinical discovery opportunities and PoC approaches - Demonstrated passion for science
Why Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
What you bring to the role:
Doctoral degree, MD strongly preferred - 5 plus years’ experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience - Significant contributions to a field over time, creates new concepts - Recognized publications record - Excellent written and oral communication/presentation skills - Independence: Able to work independently on study planning and execution, and with supervision on project planning, - Innovation: Seeks out new clinical discovery opportunities and PoC approaches - Demonstrated passion for science
Why Novartis?
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Vaccine Policy: While Novartis does not require vaccination at this time, for certain Novartis sites in the US all associates and candidates may be required to either upload an image of their COVID-19 vaccine card demonstrating proof of full vaccination for COVID-19 (or other similar evidence of vaccination) or proof of a negative COVID-19 test taken by the associate or candidate within the past seven days to enter any of our sites and/or customer office or healthcare facility, as well as prior to participating in other work related off-site meetings. Employees working in customer-facing roles must adhere to and comply with customers’ (such as hospitals, physician offices, etc.) credentialing guidelines, which may require vaccination. As required by applicable law, Novartis will consider requests for reasonable accommodation for those unable to be vaccinated. This requirement is subject to applicable state and local laws and may not be applicable to employees working in certain jurisdictions. Please send accommodation requests to [email protected].
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
NIBR
Translational Medicine
USA
Cambridge, MA
NIBRI
Research & Development
Full Time
Regular
No
