344105BR
May 05, 2022
Switzerland

Job Description

6000! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

We are looking for Scientist to join our Cell Line Screening and Development group. Our research and early development unit works with various project teams in different disease areas to express and characterize monoclonal antibodies, other therapeutic proteins and viral vectors to identify candidates with suitable developability characteristics.

What you’ll be doing
The role as Scientist is to develop and characterize mammalian recombinant cell lines for screening and production of tool and therapeutic proteins. Main tasks will encompass cell culture work at different scales, and cell based assays. In this laboratory-based role

Your responsibilities will include, but are not limited to:
• Generation of recombinant cell lines in various mammalian host cell backgrounds to enable therapeutic protein discovery and development - cell transfection, selection, and monoclonal cell line generation as well as cell line screening for productivity.
• Preparation of monoclonal cell banks as precursors for GMP cell banks, including transfer protocol preparations.
• Work in a GMP-like (DQP) cell biology and molecular biology environment.
• Interactions with Biologics Research & Development project teams and presentation of results in team meetings.
• Reporting results using electronic lab notebooks compliant with Research & Development DQP quality standards in a timely manner.
• Laboratory equipment maintenance under DQP standards.

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you’ll bring to the role:

 Background in biotechnology, cell biology, and/or Biologics drug discovery (BSc, MS or apprenticeship with 3+ years of professional experience)
 Strong technical expertise in mammalian cell cultivation (small- and mid-scale) and recombinant cell line generation.
 Strong background in cell and molecular biology.
 Desired technical expertise in flow-cytometry and automation.
 Fluency in English is mandatory, German is a plus.
 Strong team player attitude with excellent communication & interpersonal skills and capable of working semi-independently and as part of a cross-functional team.

Desirable requirements:
• Strong background in recombinant protein expression.
• Relevant academic- and/or industrial-laboratory experience with mammalian cell culture is required.
• Excellent aseptic cell culture technique is a must.
• Independent planning and execution of experiments as well as analysis of results.

You’ll receive:
• Opportunity to have hands-on experience working in a global Pharmaceutical company.
• Work and grow in a learning environment.
• Work with the latest technologies.
• Work with world class industry opinion leaders on a regular basis.

Why consider Novartis?

769 million. That’s how many lives our products touched in 2020. and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

*Some restrictions on flexible working arrangements may be applicable and will be discussed at interview as required
NIBR
BIOTHERAPEUTIC AND ANALYTICAL TECHNOLOGIES - NIBR
Switzerland
Basel
Research & Development
Full Time
Regular
No
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344105BR

Senior Scientist I - Cell Line Screening and Development (80-100%*)

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