341229BR
Mar 21, 2022
USA

Job Description

38! Soluble Biomarkers contributed to advance science in 8 First In Human and >10 Proof of Concept studies. Data contributed to demonstrate pathway engagement, proof of biology and identify the right drug and the optimal dose for the right patient! 25 innovative soluble biomarker methods were developed in >5 disease relevant tissues. 1 purpose...to reimagine medicine!

This is an exciting opportunity to join the Molecular & Cellular Sciences (MCS) team within Biomarker Development (BMD) and Translational Medicine (TM) at the Novartis Institutes for Biomedical Research (NIBR). BMD focuses on delivering fit for purpose integrated biomarkers leveraging diverse expertise and knowledge in immunology, genomics, proteomics, metabolomics and cellular biology and state of the art data sciences.
Our innovative spirit enables the development and application of cutting-edge technologies which address key clinical questions such as target engagement, defining disease stage or progression, predict the safety or efficacy of medication, select a group of patients who would benefit most from a given therapy, and identify additional clinical indications suitable for a innovative molecule.
As a Biomarker Scientist within MCS in BMD, you will work in close collaboration with project and clinical teams to develop novel exploratory assays in our state of the art laboratories, implement internal and external biomarker activities and interpret results to enable proof of mechanism, proof of biology, safety and efficacy understanding. As a soluble biomarker assay expert, you will be developing and validating innovative biomarker solutions implementing new methodologies, delivering high quality data and playing a pivotal role in human clinical trials.


Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

Your responsibilities will include, but not limited to:
What you will bring to the role:
• Ph.D in analytical chemistry, biochemistry or related discipline and must have a minimum of 3 years of hands-on experience with LC-MS using high resolution instrumentation, preferably with the Orbitrap platform; Masters with 6+ years of experience will be considered.
• Proficiency with several chromatographic separations with emphasis on Ultimate 3000 nano and other UPLC systems.
• Expertise in the acquisition and analysis of untargeted metabolomics data.
• Demonstrated experience in LC-MS based methods including sample preparation, data acquisition, and data analysis comprising quantitation of features across samples, metabolite identification.
• Experience with both commercial and open sources software tools for bioinformatic analysis and visualization of data from metabolomics experiments.
• Experience in troubleshooting of LC and MS systems
• Experience with lipidomics is a plus.
• Illustrated ability to be creative, self-motivated, work collaboratively and independently.
• Analytical thinking, willingness to accept responsibility, and teamwork skills
• Good communication skills for oral and written in English



Why Consider Novartis?

766 million. That’s how many lives our products touched in 2021. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and
empowers our people to unleash their full potential.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here:
https://talentnetwork.novartis.com/network

We are Novartis. Join us and help us re-imagine medicine.
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NIBR
Translational Medicine
USA
Cambridge, MA
Research & Development
Full Time
Regular
No
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341229BR

Biological Mass Spec Scientist - BMD, Translational Medicine

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