Feb 11, 2022

Job Description

4 FDA approved drugs; 15+ clinical candidates; 400+ patents; more than two decades making of history! For over 21 years, the Novartis Institute for BioMedical Research (NIBR San Diego) has been doing cutting-edge innovative drug discovery.

Join us to make a difference in the next twenty years!

The Biotherapeutics Department, Structural Biology Group is looking for a highly motivated Senior Scientist, skilled in Protein Science to support computational and experimental Protein Design on novel protein biotherapeutics. The successful candidate will work as part of a multi-disciplinary team to characterize computational engineered proteins via high-throughput protein expression, purification and biophysics.

Primary responsibilities:
• Small and medium scale protein production for utilization in biophysics, assay and structure applications.
• Experimental support for the development of computational protein design methodologies and assays.
• Communication and presentation of scientific and technical work to colleagues.
• Collaboration with scientific teams across the San Diego and global Novartis sites


Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:
• BS/MS in biochemistry or related field
• 4 years of experience with molecular biology techniques.
• Expertise in E. coli protein expression. Knowledge of other expression systems such as yeast, mammalian or insect is advantageous but not required
• A practical understanding of protein purification techniques and instrumentation (gravity, FPLC, HPLC, NTA, SEC and RP )
• Familiarity of biophysical methods (SPR, CD, light scattering, ITC and DSC ) and laboratory automation is preferred.
• High degree of self-motivation and attention to detail
• Strong organizational and time management skills
San Diego, CA
Research & Development
Full Time
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Senior Scientist - Protein Science

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