Jan 17, 2022

Job Description

>40 years of expertise in biotech production and cutting-edge process development and a growing product portfolio including protein, pDNA and mRNA molecule formats including molecules relevant in the light of the COVID-19 pandemic. The highly diverse development pipeline creates unique opportunities within our process development teams to solve scientific and technical challenges in innovative drug substance and cell and gene therapy technical development programs.

As Principal Scientist Upstream Process (USP) Development (f/m/d) you will be part of a young, cross-functional R&D organization for development of microbial manufacturing processes covering the full spectrum of Novartis biologics and cell and gene therapy pipeline.

Your responsibilities include, but are not limited to:
• You will act as functional expert for upstream process development and lead the USP sub-team for the assigned project(s) for nucleic acids, biosimilars and/or new biological entities in alignment with interface functions (e.g. DSP, analytical development, QA)
• Design, plan, perform, interpret and document scientific experiments for the development of upstream processes with microbial hosts for recombinant proteins and nucleic acids, to achieve efficient, scaleable and robust manufacturing process
• Characterize and transfer processes and support process validation and registration of the product
• Set priorities for the team; support the growth of USP team members and motivate them as appropriate by an encouraging and servant leadership
• Proactive identification of scientific, technological and operational challenges, propose creative solutions and communicate key issues to internal and external customers and stakeholders
• Key member of the Cell and viral vector development’s drug substance development organization participating in strategic and operational decision-making processes

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Minimum Requirements

What you’ll bring to the role:
• Master Degree in biotechnology, biochemical engineering, biology, chemistry, biochemistry or similar
• Experience in biopharmaceutical industry: Master: 4+ years, PhD: 2+ years

• Excellent command of spoken and written English language skills
• Thorough understanding of cultivation of microbial cells (mainly bacteria and yeasts) and production of proteins and nucleic acids;
• Excellent theoretical and scientific knowledge in the relevant area of expertise including proficiency with technical equipment
• Scientific project management and leadership skills as well as presentation skills
• Thorough understanding of isolation (from microbial cells) and purification process development for proteins and nucleic acids

Desirable requirements:
• Excellent organizational skills, team player, agile and dedicated personality
• Excellent problem solving mind-set, attitude to resolve challenges, interdisciplinary thinking.
• Ability of properly balancing between efforts, risks and benefits

Why Novartis?
769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

In addition to a market-competitive base salary, we offer an attractive incentive program, a modern company pension scheme, childcare facilities, learning and development options as well as worldwide career opportunities within the Novartis group. In accordance with Austrian law, we are obliged to disclose the minimum salary as stated in the collective bargaining agreement. For this position the minimum salary is € 51,180.50/year (on a full time basis). In most cases, the actual salary will be higher, as we strive to maintain a competitive position in the market and consider your previous experience, qualifications and individual competencies.

Commitment to Diversity & Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

Our recruitment decisions are based on selecting the best person for the job, regardless of gender, religion, age, colour, race, sexual orientation, nationality or disability.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
Global Drug Development
Research & Development
Full Time
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Principal Scientist (f/m/d) – Upstream Process (USP) Development

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