334811BR
Jan 12, 2022
USA

Job Description

750 million+. That’s the number lives our products touch. While we’re proud of that fact, in this world of digital and technological transformation, we must continue to improve and extend even more people’s lives. We believe we can achieve the goal when curious, courageous and collaborative people like you are brought together in an inspiring environment, empowering you to take calculated risks, and teaming you with people who share your determination, to tackle the world’s toughest medical challenges.

We have an exciting new opportunity for a Director Pharmaceutics to lead strategy for clinical development programs. In this role, you will drive the design and implementation of methodologies that help optimize drug development programs at the Development Unit and/or disease area level and manage a portfolio. You have an opportunity to lead and integrate input from different quantitative scientists impacting clinical development, health authority interactions and represent the PMX function at internal and external decision boards, develop and mentor other pharmacometricians, and provide strategic, technical, operational and scientific leadership and solutions to the organization.

What you’ll be doing:
• Lead the PMX contributions to the integration of relevant technical and disease area knowledge in the planning and execution of robust development programs.
• Represent the development unit internally and externally as the pharmacometrics expert, including regulatory interactions.
• Foster the integration of pharmacometric methodology into clinical development programs, and ensure that the Analytics team (biometrician, data management, database programming, programming, medical and scientific writing) are aligned on the pharmacometric strategy, its execution and delivery.
• Anticipate needs for PMX and strategic support at the disease/therapeutic area levels.
• May manage portfolio at Disease/Therapeutic Area level to support integration of pharmacometrics and relevant (target, compound, disease) knowledge in the planning and execution of robust development programs and strategies, independently but in coordination with the PMX Development Unit leader.
• Lead or significantly contribute to initiatives at global line function level, or cross-functional Development Unit level, requiring coordination of diverse of team members.
• Lead the review and implementation of Health Authority guidances
• Develop and mentor pharmacometricians.
• May have 6 PMX scientists direct reports providing support to the disease/therapeutic area.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• Ph.D. in pharmacology, biology, engineering, mathematics, statistics, computational science, or a field with significant modeling-related content (or equivalent) with 8+ years relevant work experience; 6+ years in applying, and mentoring model based methods in pre-clinical and clinical drug development.
• Track record of identifying and leading contributions to external white-papers/policy that shape best practice in pharmacometrics. Has internally and externally established track record of developing/establishing pharmacometrics excellence. Record in contributing to scientific improvement/change initiatives.
• Expert knowledge and evidence of hands-on experience in the application of pharmacometrics methods to drug development
• Evidence of consulting skill in the drug development context, i.e. within project teams and management boards; experience interacting with regulatory agencies.
• Clinical, pharmacological and therapeutic knowledge in one or more disease areas
• Proven expert scientific leadership skills demonstrated in facilitating and optimizing the (pre/early/full-) clinical development strategy.
• Fluent in English (oral and written)

Highly Desirable:
• Excellent communication and presentation skills and in particular the ability to effectively represent pharmacometrics issues to a wide range of target audiences.

Location: This position can be based out of East Hanover NJ, Cambridge, MA or Basel, Switzerland
You’ll receive:
Competitive salary, annual bonus, pension scheme, share scheme, health insurance, 25 days annual leave, flexible working arrangements, subsidized dining facilities, employee recognition scheme and learning and development opportunities as well.

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Novartis is an equal opportunities employer and welcomes applications from all suitably qualified persons.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here:

https://talentnetwork.novartis.com/network

Why Novartis?
769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
Global Drug Development
CD&A GDD
USA
East Hanover, NJ
Switzerland
Research & Development
Full Time
Regular
No
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334811BR

Director / Senior Director Pharmacometrics

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