Mar 25, 2022

Job Description

Approximately 60 million adults in the US experience mental illness in a given year. In about 13 million of these patients, the illness is severe and substantially interferes with one or more major aspects of their lives. Here, at the Neuroscience department at Novartis Institutes for Biomedical Research, we are looking for highly motivated researcher with experience in electrophysiology, to join a multidisciplinary team committed to finding and improving treatments to better the lives of these patients.

This is primarily a lab-based position in which the successful candidate will be responsible for developing and/or conducting established in vitro electrophysiological assays and experiments, ranging from ion channel function in stable cell lines to synaptic transmission in brain slices and organoid slices, to characterize molecules for potential therapeutic effects. You will also be involved in new target discovery and validation as well as investigating the mechanism of action of potential drug candidates.

Your responsibilities will include:
• Analyzing, interpreting, organizing, and presenting your results (verbally and/or in written format) to project team members, relevant research staff and the Neuroscience Department as needed
• Monitoring inventory and ordering relevant laboratory reagents and supplies
• Managing necessary aspects of experimental resource requirements
• Performing routine maintenance and calibration on specialized equipment used in your research
• Learning new techniques and approaches as needed to tackle key scientific questions.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you'll bring to the role:
• A minimum of a Bachelor’s degree in Neuroscience, Biophysics, Biomedical Engineering or related discipline
• A minimum of three years of laboratory-based industrial or academic experience
• Previous, hands-on exposure to in vitro electrophysiology, including but not limited to patch clamp and/or extracellular field potential recordings as well as high throughput electrophysiology platforms and assays. Priority will be given to candidates with demonstrated proficiency in acute brain slice electrophysiology.
• Experience and/or comfort working with rodents, primary neuronal cultures and cell lines
• A self-motivated and pro-active attitude, with the ability and desire to multi-task
• Solid work ethics and demonstrated record of productivity
• A results-driven mentality with a sense of urgency and commitment to the goals of our mission
• Ability to focus and pay attention to detail
• Recognize and troubleshoot data anomalies to maintain high data quality (after appropriate training, if required)
• Intermediate/advanced experience with MS Office and ability to learn new software
• Excellent problem solving, organizational and experimental management skills
• Strong written and verbal communication skills
• Commitment to help the team achieve deliverables and meet aggressive timelines
• Ability to be both independent as well as effectively interact with team members and work in a highly dynamic and collaborative environment
• Scientific curiosity, technical excellence, superb organizational skills, and an enthusiastically collaborative spirit are qualities we highly seek.

Additional, desirable qualifications:
• Familiarity with neuroscience concepts, including the general mechanisms underlying synaptic transmission and ion channel function
• Experience with the preparation of organotypic brain slice cultures
• Experience with molecular cloning, immunostaining and imaging approaches
• Familiarity with basic statistical analyses and how to apply these to biological data
• Experience performing surgical procedures, with particular emphasis on intracranical virus injections and/or in utero electroporation
• Experience working with scientific/analytical software packages/platforms (e.g. IGOR Pro, MATLAB, Python, R). Programming experience is a big plus.
• Flexibility and willingness to occasionally adjust your hours as required by specific experiments

769 million lives were touched by Novartis medicines in 2020 and, whilst we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life is the risk of never trying! Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.Novartis.com/network
Cambridge, MA
Research & Development
Full Time
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Cellular Neurophysiologist

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