Research Scientist, Neurobiology

Oct 06, 2021

Job Description

1 in 15 people worldwide could be affected by a rare disease: that’s more than 400 million people all over the world! As a Research Scientist in the Rare Diseases Unit of the Neuroscience department, you will have an opportunity to develop innovative medicines that can improve lives and health of patients suffering from rare genetic diseases.

We are seeking a highly motivated scientific associate with a strong background in the fields of cellular and molecular neurobiology to join our team. The candidate will assume a hands-on role to design and conduct in vitro and ex vivo studies in support of the discovery and characterization of therapeutics for rare genetic neurodevelopmental disorders.

Key Responsibilities:
• Prepare primary mouse neuron and iPSC-derived neuron cultures
• Develop and perform cellular and molecular assays including but not limited to western blot, ELISA, qPCR, immunofluorescence imaging, multi-channel array recording to characterize cellular models of disease and perform proof of concept studies for new therapeutic candidates
• Perform in vivo procedures in rodents (perfusion, tissue dissection, and blood collection) to support project needs
• Execute experiments to meet project timelines and objectives
• Thorough and timely documentation of experimental protocol and results using electronic lab notebook (ELN)
• Analyze and present results to project teams and at lab and department meetings

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you'll bring to the role:
• BS or MS in biological science with 2+ years experience of academic or industry laboratory research
• Hands-on experience with in vitro methods including mammalian cell culture and molecular biology techniques such as western blotting, ELISA, qPCR, IF
• Prior experience with performing in vivo procedures in rodents, including perfusion, tissue dissection, and blood collection, is a plus
• Knowledge of molecular and cellular neurobiology and associated methodologies is a plus
• Flexibility and aptitude for learning, with the ability to quickly grasp new techniques and apply them to work
• Ability to multi-task, work collaboratively as well as independently
• Excellent communication and presentation skills, and the ability to work optimally in a matrixed team environment

Desirable Requirements:
• Experience in Imaging and image analysis skills
• Familiarity with molecular and cellular pathways in neurodevelopmental disorders

Why Novartis?
769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here:
Cambridge, MA
Research & Development
Full Time
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Research Scientist, Neurobiology

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