Senior Expert Mass Spectrometry (80-100%)

328746BR
Oct 12, 2021
Switzerland

Job Description

200! The approximate number of Clinical Development projects currently in the Novartis pipeline. Many of these projects, which include new biological entities, are for medicines that could significantly advance treatment standards for patients worldwide.

We are looking for a Senior Expert to join the Analytical Characterization (AC) team in Basel, Switzerland. Within analytical characterization in biologics development, Novartis new biological entities (NBEs) are supported from proof-of-concept in human (i.e. finalization of the first phase I clinical trial) to commercialization and up to life-cycle management activities. AC applies a wide range of physico-chemical analytical techniques to characterize the biopharmaceutical products with regards to their purity, identity, and structural integrity. The AC team is an integral part of the global Analytical Development unit, which is part of Novartis Technical Research and Development (TRD). The applicant will be part of the mass spectrometry group working in a highly collaborative and scientific environment. The successful applicant will work in close interaction with other experts in the analytical community.

Responsibilities will include but are not limited to:
• Characterization of therapeutic proteins, their post-translational modifications, degradation products and impurities (e.g. host cell proteins) by mass spectrometry (MS) using innovative LC-MS equipment
• Comparability assessment of drug substances/drug products
• Development of MS related methods and implementation of new technologies for the effective characterization of biopharmaceuticals
• Maintenance and qualification of lab equipment

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

Minimum Requirements

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.
Global Drug Development
TECHNICAL R & D GDD
Switzerland
Basel
Research & Development
Full Time
Regular
No
328746BR

Senior Expert Mass Spectrometry (80-100%)

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