Principal Scientist, Viral Technology

328321BR
Oct 15, 2021
USA

Job Description

6000! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. NIBR Biologics Center (NBC) builds the biologics pipeline in collaboration with NIBR Disease Areas and Platforms via a breadth of technologies for discovery of antibody, protein and gene therapy-based therapeutics.

We are seeking a Principal Scientist specialized in viral gene therapies with an emphasis on AAV to join the Biotherapeutic Engineering and Gene Therapy (BEGT) group within NBC in Cambridge, Massachusetts. The BEGT group drives a diverse portfolio of modalities including therapeutic proteins, multi-specific antibodies, CAR-T, RNA therapeutics and AAV. Through innovative and rational protein design as well as cell and viral engineering, the BEGT group works collaboratively within NIBR to broaden the use of biologics into therapeutic applications where conventional antibodies have limitations.

Your key responsibilities are, but not limited to:
• Design and perform experiments independently to address key scientific questions in the AAV gene therapy field.
• Bridge eukaryotic gene expression expertise, conjugation and capsid engineering to bring the next generation of gene delivery platforms into the pipeline.
• Work collaboratively to lead synthetic biology activities and contribute to gene therapy platform and pipeline.
• Establish in vitro cell based assays to support gene therapy research.
• Contribute to NBC’s viral production activities at research scale (discovery through NHP).
• Collaborate with Disease Area colleagues to address unmet technology needs with well-designed experiments and execution.


Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
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NIBR
BIOTHERAPEUTIC AND ANALYTICAL TECHNOLOGIES - NIBR
USA
Cambridge, MA
Research & Development
Full Time
Regular
No
328321BR

Principal Scientist, Viral Technology

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