Sr. Scientist, Ophthalmology - Gene Therapy

328309BR
Sep 23, 2021
USA

Job Description

The Ophthalmology department at the Novartis Institutes for BioMedical Research (NIBR) is seeking an experienced, talented, motivated scientist to join the gene therapy unit in our mission to develop transformative AAV-based gene therapies to treat patients with blinding diseases.

The successful candidate will have strong technical skills in molecular biology, cell culture and cell-based assays, a proven track record of productive, independent work, and a commitment to working toward a common goal. The candidate will work collaboratively with groups in the Ophthalmology Disease Area and across divisions at NIBR. This individual will report findings effectively by oral and written presentation. Applicants should possess excellent record keeping and organizational skills. Excellent communication and teamwork are critical to success in this position.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role;

•BS/MS with 3-4+ years of industry laboratory experience
•Proficient execution of standard molecular, and cell biology techniques including cloning, PCR, DNA sequencing, RT-qPCR, Western blotting, transfection, ELISA, and/or ddPCR.
•Assess potency of AAV-mediated transduction in-vitro or ex-vivo via immuohistochemistry, RNA expression, Western blotting, or functional readout.
•Demonstrated expertise in cell-based assays and/or assay development
•Experience in iPS cell line differentiation and/or stable cell line generation
•Work independently to design and interpret experiments and plan next steps
•Clearly present results and data to teams
•Work in compliance with the Novartis Code of Conduct and in accordance with Novartis guidelines on health and safety and data recording
Additional desirable qualifications:
•Training in ophthalmology and genetics
•AAV or lentiviral production, purification and characterization
•Familiarity with ex vivo experimentations such as tissue microdissection, sectioning, IHC staining or explant cultures

799 million. That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
NIBR
OPHTHALMOLOGY
USA
Cambridge, MA
Research & Development
Full Time
Regular
No
careers default image
328309BR

Sr. Scientist, Ophthalmology - Gene Therapy

Apply to Job Access Job Account