Bioinformatics Research Scientist, Oncology Data Science

Sep 20, 2021

Job Description

Over 35 preclinical targets in our pipeline! Novartis Institutes for BioMedical Research (NIBR) Oncology strives to reimagine medicines for cancer patients through a combination of treatment approaches including targeted therapies, immunotherapies, CAR-T, and radioligand therapy!

Oncology Data Science is seeking a computational biologist to work closely with both other data scientists and wet lab members of the oncology team, as you explore our extensive characterization of thousands of preclinical models using machine learning, help design and analyze new groundbreaking ‘omics assays with NGS know-how, and open up the boundaries in research for discovering new targets and combinations in a range of cancer indications. The successful candidate will be highly motivated, creative, curious, collaborative, and excited to join a team working to cure cancer.


• Implementing and developing state-of-the-art computational methods and data mining strategies to address key challenges in oncology drug discovery including drug resistance, tumor heterogeneity, and ways to tackle difficult-to-drug targets
• Working closely with wet and dry lab collaborators to analyze and interpret high-dimensional data such as CRISPR screens, single-cell RNAseq, and proteomics
• Analyzing and integrating large proprietary internal data from bespoke assays with public resources such as CCLE, TCGA, and DepMap
• Supporting translational genomics, model characterization, and data mining efforts to seek unmet medical needs
• Formulating testable hypotheses and collaborating in the design of rigorous experiments.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:

• MS (or BS with equivalent experience) in computational biology, bioinformatics, systems biology, biostatistics, computer science, or related field
• An understanding of the fundamental concepts in bioinformatics, statistics, and cell biology preferably in an oncology environment
• Proven excellent data visualization and interpretation skills and ability to communicate optimally with partners and bioinformatics colleagues
• Ability to evaluate and apply sophisticated mathematical and computational concepts to problem-solving situations
• Proficiency in R or Python; competency working in a Linux environment; experience with bioinformatics tools (e.g. Bioconductor, bwa) and biological databases (e.g. MSigDB, GO, PDB)

Why consider Novartis?

769 million. That’s how many lives our products touched in 2020. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Commitment to Diversity & Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Oncology NIBR
Cambridge, MA
Research & Development
Full Time
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Bioinformatics Research Scientist, Oncology Data Science

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