Research Scientist II, Radiochemistry (* 80-100%)

Oct 04, 2021

Job Description

700! That’s the number of talented chemists within Global Discovery Chemistry (GDC) at the Novartis Institutes for Biomedical Research (NIBR) who design and make new molecules for treating patients.

In Global Discovery Chemistry (GDC) at the Novartis Institutes for Biomedical Research (NIBR) in Basel, Switzerland, we are at the core of Novartis’ purpose. We are looking for a highly motivated, passionate researcher with a strong scientific background in radiochemistry or related disciplines, a curious mind-set, and cultural agility to work in a highly dynamic team to identify new targeting vectors for radioligand therapies (RLT). Join us and help reimagine medicine!

Your responsibilities will include, but are not limited to:
• You will independently plan and execute the synthesis of Ga-68 and Lu-177 radioligands (peptides and/or proteins) as part of a dynamic team of associates according to a program defined by the project team.
• You will propose, evaluate, interpret and validate new radiolabeling procedures with radioisotopes including the use of automation and advanced formulation development.
• You will collect and perform the quality control of radioligands by High Performance Liquid Chromatography (HPLC), Radio Thin Layer Chromatography (R-TLC), Liquid Chromatography/Mass Spectrometry (LCMS) and Size Exclusion Chromatography (SEC) in the radiochemistry lab environment and release the radioligands for preclinical studies.
• You will be responsible to implement radiation safety regulations, (e.g. trainings, dosimetry, release of radioactive wastes).
• You will evaluate novel technologies including possibilities for automation to make the daily work more efficient.
• You will collaboratively work in a multidisciplinary project team to characterize novel radioligand therapies in the oncology disease area.

Diversity & Inclusion / EEO

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

Minimum Requirements

What you will bring to the role:
• MSc, BSc or apprenticeship qualified with a focus in radiochemistry and radiolabeling or related subject area.
• You will have 2-5 years practical experience in radiochemistry/radiolabeling and profound knowledge of standard IT applications (e.g. E-Notebook, ChemDraw, software controlled lab equipment).
• A passion for hands-on radiochemistry experimentation in the laboratory with the ability to critically interpret results, build new experimental hypotheses, and take smart decisions.
• The ability to learn new radiochemistry techniques, specific practical analytical techniques and apply this knowledge to solve technical problems
• A mind-set of curiosity, creativity and willingness to diverse thinking, with an enthusiasm to develop yourself also beyond your current comfort zones.
• An organized working style, eye for detail, flexibility and commitment to high quality.
• A desire to collaborate with a highly dynamic team, discuss science and contribute to the next generation of RLTs.
• Excellent oral and written communication in English and applications in German are welcome too.

*Some restrictions on flexible working options may apply and will be discussed during interview if applicable.

Why consider Novartis?
769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working. We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here:
Global Discovery Chemistry
Research & Development
Full Time
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Research Scientist II, Radiochemistry (* 80-100%)

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