Principal Scientist, Synthetic Chemistry

Sep 10, 2021

Job Description

8! The number of disease areas you will impact when collaborating across Novartis Institutes for BioMedical Research (NIBR). At Novartis, we are reimagining medicine to improve and extend people’s lives.

We have an exciting opportunity within our Synthesis Technologies Team to impact across multiple disease areas at NIBR. We use innovative science and technology to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. How can we continue to advance our science to help even more patients in need? We believe the answers are found when curious, courageous, and collaborative people are empowered to ask new questions, make bolder decisions, and take smarter risks.

In Global Discovery Chemistry (GDC) at the NIBR in Cambridge, USA, we are at the core of Novartis’ purpose. We are looking for a highly motivated, passionate synthesis expert with a strong background in chemistry, a curious mind-set, and the cultural agility to invent innovative medicines and advance the frontiers of drug discovery. Join us and help reimagine medicine!

Your responsibilities will include:

As a synthesis expert, contribute to innovative solutions by identifying and addressing synthetic challenges, in order to drive the success of projects across GDC. Specifically....

- Design and execute robust synthetic routes to access novel chemical scaffolds.

- Identify gaps in existing synthesis methodologies and seek to leverage Technology solutions to directly address these through internal and external partnerships.

- Apply cutting edge synthesis planning tools to identify strategic approaches, facilitating new project opportunities in Lead Optimization.

- Skillfully navigate challenges to ensure rapid advancement of Discovery Candidates under tight timelines (multi-gram scale).

- Work within a matrixed environment to define and execute material supply strategies, combining both in-house and external resources.

- Build strong networks, identifying and facilitating solutions for chemists across the globe.

- Mentor, coach, and support the growth of associates as a leading synthesis expert.

- Communicate results at project meetings and external conferences.

- Contribute to publications and patent applications.

- In addition to pipeline project responsibilities, participate in global initiatives shaping the future of drug discovery at NIBR

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:

- Knowledge consistent with a PhD completed in synthetic organic chemistry with excellent theoretical and broad practical experience in small molecule chemistry, or BS/MS level degree with significant industrial experience in a synthesis-focused role (including scale-up experience).

- Proven record of accomplishment in initiating, leading, or being a key contributor to innovative research in chemistry. Excellent oral and written communication and strong influencing skills

- In-depth understanding of synthetic problem solving and purification methodologies, including up-to-date knowledge of relevant literature. Strong passion and drive for chemistry experimentation in the laboratory.

- A curious, creative and collaborative mindset, open to diverse problem solving approaches. Ability to critically interpret results, build new experimental hypotheses, and take pragmatic risks.

- A passion for continued learning with an enthusiasm to develop yourself and others.

Why consider Novartis?

769 million. That’s how many lives our products touched in 2020. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

Here, where we value your ideas, personal growth and career aspirations; you will be surrounded by and learn from curious, unbossed colleagues across multiple disciplines; you will be empowered to take smart risks, and to use your creativity and tenacity to work towards creating the next pharmaceutical.

We are Novartis. Join us and help us reimagine medicine.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Global Discovery Chemistry
Cambridge, MA
Research & Development
Full Time
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Principal Scientist, Synthetic Chemistry

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