Senior Scientist, Chemistry, Chemical Biology and Therapeutics

Sep 09, 2021

Job Description

5600! That is the number of associates across the globe at the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

The Chemical Genetics group in Cambridge, MA, is seeking a highly motivated, curious, and innovative scientist to boost our endeavor in the discovery, development, and characterization of small molecules affecting defined phenotypes with the goal of uncovering and validating novel therapeutics and drug targets. We are a highly collaborative and global group of chemists and biologists dynamically exploring the interface of chemistry and biology in initiating, leading, and progressing projects in early drug discovery. This group is part of the larger Chemical Biology and Therapeutics (CBT) department that encompasses the full-spectrum of sophisticated capabilities needed to succeed in a state-of-the-art drug discovery biopharma laboratory. This position will partner closely with research teams within CBT, as well as across diverse Disease Areas.

Your responsibilities include, but are not limited to:

- Embracing a chemical biology mentality to scout, develop, and apply groundbreaking chemical biology techniques, for discovery of new therapeutic approaches, targets, and modalities.

- Small molecule design, synthesis and optimization, including exploration of structure activity relationships and synthesis of chemical probes for addressing impactful biological and conceptual questions.

- Apply molecular-level thinking and research tools to elucidating LMW-gene relationships in defined phenotypes advancing novel therapeutic modalities.

- Working in multi-disciplinary teams to integrate expertise across NIBR to contribute to and progress novel drug discovery projects.

- Frequent oral data communication/presentation across a spectrum of skillsets and levels, engagement of internal and external partners and collaborators.

- Organizational skills for design, tracking, and communication experiments and data.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:

- Recent Ph.D., or MSc and 7+ years of proven experience in academia or industry, with demonstrated ability in one or more of the following: synthetic organic chemistry, drug discovery, chemical biology, chemical probe design, novel modalities such as RNA biology or targeted protein degradation.

- Proficiency in broad array of chemical synthesis techniques, chemical probe design and development, characterization and purification of new molecular entities/modalities.

- Experience with of a broad array of integrated chemical biology research tools for target identification.

- Experience in mentoring, advising, and guiding research execution of laboratory experiments of junior associates, CROs.

- Track record of innovation, efficient hypothesis testing, and execution of outside-the-box approaches to tackle ambitious scientific problems.

- Ability to design, perform, analyze, and interpret data to propose next steps in both experimental and project design and overall strategy.

- Highly self-motivated, fast learner, flexible, innovative and fearless.

- Thrives in an interdisciplinary, collaborative environment

Why consider Novartis?

799 million. That’s how many lives our products touched in 2019. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Cambridge, MA
Research & Development
Full Time
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Senior Scientist, Chemistry, Chemical Biology and Therapeutics

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