Research Scientist (BS/MS), Cell and Molecular Biology, MSD

Sep 01, 2021

Job Description

1. That's the number of current viral gene therapy treatments approved by the FDA and EMA for any neuromuscular disease. Novartis’ AAV gene therapy approved for the treatment of spinal muscular atrophy offers patients a transformative option in their fight with this devastating disease. Novartis Institutes for Biomedical Research and the Musculoskeletal disease area are committed to development of the next generation of life saving medicines for the world’s most severe medical disorders.

We are seeking a talented and self-motivated scientist to join our preclinical stage research group in Cambridge, MA. As part of a team, the successful candidate will design and conduct in vitro and cellular studies in support of the discovery and characterization of therapeutics (low molecular weight, biologics and gene therapy) for musculoskeletal and neuromuscular diseases.

Responsibilities will include, but are not limited to:

- Perform molecular biology techniques to support proprietary gene therapy platform technologies for the creation of new therapeutic candidates.

- Apply a diversity of in vitro techniques to identify and validate assays, characterize cellular models of disease and assess preclinical samples for pharmacodynamic biomarkers ex vivo.

- Generate, analyze and document study results, as well as interpret and present data to multidisciplinary groups.

- Keep current on emergent technologies through literature review and scientific meetings.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What You'll Bring to the Role:

- MS, BS or equivalent degrees in the life sciences with 4+ years of demonstrated ability, preferably in industry.

- Expertise in in vitro methods including but not limited to molecular and cellular biology. Viral vector techniques are desirable.

- Knowledge and hands-on experience in developing and implementing assays (e.g. cell culture, qPCR, IHC/IF, ELISA, gene and protein analysis, imaging).

- Prior experience with induced pluripotent stem cell cultures (musculoskeletal and/or neuromuscular disease models an advantage).

- Ability to document, organize, communicate and present sophisticated data sets to multidisciplinary groups.

- Ability to multi-task, work collaboratively as well as independently, be scientifically curious and self-motivated

- Excellent oral and communication skills, analytical skills and interpersonal skill

Why consider Novartis?

769 million. That’s how many lives our products touched in 2020. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Cambridge, MA
Research & Development
Full Time
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Research Scientist (BS/MS), Cell and Molecular Biology, MSD

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