Senior Principal Scientist

Jul 23, 2021

Job Description

15! The number of collaborative scientists in our group who are committed to translating scientific innovation into medicines. We are not afraid to tackle the most complex therapeutic challenges of today, and we know that the only way to do it is together.

Come join us in the oncology-focused Biological Chemistry Group at the Novartis Institute for Biomedical Research (NIRB). At NIBR, we are purposeful about deploying one-of-a-kind resources and cutting-edge technologies to make meaningful impact.

Your responsibilities will include, and are not limited to:

• Applying fundamental principles of biochemistry and biophysics toward target understanding and small molecule drug discovery
• Leading within NIBR’s highly matrixed small molecule drug discovery engine to implement hit ID, hit confirmation, hit-to-lead and lead optimization strategies.
• Mentoring and developing a team of a minimum of 2 direct reports.
• Independently providing biochemical and biophysical domain expertise on cross-functional teams.
• Contributing to early target ID and validation.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

• A minimum of a PhD with 6+ years or a master’s degree with 10+ years of industry-based drug discovery experience
• Demonstrated ability to tackle complex problems and refine target modulation hypothesis
• Prior exposure to multiple mechanisms of action of small molecule drug candidates
• Working knowledge of cross-functional disciplines (e.g. structural biology, protein sciences, pharmacology)
• Demonstrated commitment to directly or indirectly mentoring and guiding career development of junior team members

Commitment to Diversity & Inclusion:

Novartis is committed to building an outstanding, inclusive work environment and diverse team’s representative of the patients and communities we serve.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Oncology NIBR
Cambridge, MA
Research & Development
Full Time
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Senior Principal Scientist

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