Principal Scientist, In Vivo Ophthalmology

Jul 15, 2021

Job Description

60 million! That is how many people are affected globally by glaucoma. This progressive disease can lead to damage of the optic nerve and eventually lead to blindness. At the Novartis Institutes for BioMedical Research (NIBR), we are developing new therapies to help control disease progression by lowering intraocular pressure and providing neuroprotection in the hope of finding a cure for this silent thief of sight.

We are looking for a Principal Scientist to join our Ophthalmology Department to support the discovery and development of innovative treatments for glaucoma and other ocular diseases. In this role, you will serve as an in vivo pharmacology expert responsible for conceptualizing, generating and characterizing in vivo models of disease. This includes effectively leading a team of scientists, and potentially a project team, in an innovation-based role across a matrixed organization.

What you will be doing:

•Perform experiments, analyze data, generate written and oral reports, and stay current with the literature and technological advances
•Effectively lead a team of scientists through both scientific and career growth mentoring
•Utilize novel and established in vivo models to test compounds using pharmacodynamic readouts
•Demonstrate proficiency in surgical techniques, tissue staining, and microscopy
•Collaboratively generate hypotheses with cross-functional teams and validate targets
•Identify new relevant techniques and platforms with a strategic focus impacting drug discovery in Ophthalmology research

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you will bring to the role:

•Ph.D. with a completed post-doctoral fellowship and/or 3-5 years of laboratory experience in an industrial or academic setting with mentorship/people management experience
•History of developing and characterizing in vivo models of disease
•Demonstrated history of self motivation, team work, independent contributions and leadership with a strategic focus
•Demonstrable experience in solution-minded and data-driven decision-making
•Interest and ability to apply methods such as genecards, multiplexed ELISAs, RNAseq etc. for model characterization and biomarker/pharmacodynamic hypothesis generation

What Novartis can offer you?

Yes, we offer exceptional benefits and competitive salaries. However, we can offer more. Here you will:

•Work with the latest technologies and talented scientists

•Take a leadership role in advancing treatment for ocular diseases

•Join an organization that is committed to your development and advancement

Why consider Novartis?

Transformative medicines need transformative thinking. We believe the answers are found when curious, courageous, and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here:
Cambridge, MA
Research & Development
Full Time
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Principal Scientist, In Vivo Ophthalmology

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