Scientist or Senior Scientist, Antibody Characterization

315195BR
USA

Job Description

6000! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Novartis Biologics Center (NBC) discovers and develops biologic therapeutics to treat unmet medical needs in all of Novartis’s disease areas – oncology, autoimmune, respiratory and cardiovascular diseases.

We are in Scientist with experience in biologics discovery to join our team. In this role, you will have direct experience in antibody characterization by surface plasmon resonance (Biacore or ProteOn), binding characterization by other approaches (Fortebio, Kinexa) flow cytometry, LigandTracer and functional assay development (ELISA). You will collaborate with other scientists to characterize and identify lead molecules as biotherapeutic drugs candidates.

What you’ll be doing:
• Design Biacore methods including direct immobilization and capture formats to assess protein-protein interactions
• Analyze and interpret Biacore data with the ability to draw own conclusions in alignment with project initiatives
• Work in other binding technologies to assess soluble protein-protein interactions (e.g. ProteOn, Fortebio), mammalian cell culture and cellular binding technologies to characterize antibody molecules binding to cells (e.g. Kinexa, LigandTracer)and protein analytical techniques including SDS-PAGE, Western blotting to QC protein reagents
• Collaborate in research teams where data needs to be clearly compiled in a slide deck and effectively presented to the team
• Generates hypotheses to test, troubleshoots issues, designs and executes the next set of experiments with some input from senior lab members
• Provides basic data analysis to interpret own experiments - assesses whether experimental hypothesis was appropriately tested and answered.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
NIBR
BIOTHERAPEUTIC AND ANALYTICAL TECHNOLOGIES - NIBR
USA
Cambridge, MA
Research & Development
Full Time
Regular
No
careers default image
315195BR

Scientist or Senior Scientist, Antibody Characterization

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