ADME Scientist, Assay Development

315116BR
Sep 20, 2021
USA

Job Description

9 Billion! The amount Novartis invests in Research & Development. The Novartis Institutes for BioMedical Research (NIBR) is the innovation engine of Novartis. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. the lives of millions.

As an ADME Scientist, Assay Development with NIBR's PK Sciences organization you will facilitate the ADME optimisation of next generation of new modality therapeutics. Growing the area of new modality therapeutics is part of the longer-term strategic plan and investment of Novartis, this is an opportunity to help bring new and innovative products to those in need.

The discovery absorption, distribution, metabolism, and excretion (ADME) group within the Pharmacokinetic Sciences (PKS) Department at the Novartis Institutes for Biomedical Research (NIBR) is seeking a highly qualified multi-disciplinary team-oriented Scientist having cell biology experience with emphasis on in vitro ADME assays. In this role you will provide support for a diverse portfolio that includes small molecules, antibody-drug conjugates, targeted bi-functional degraders, and other molecules in the beyond rule-of-5 property space.

You will also be responsible for the troubleshooting and development of new ADME cell-based assays and/or running existing in vitro ADME assays to support pre-clinical project teams. You should have the ability to conduct cell culture experiments, and experience investigating the fate of molecules in the beyond rule-of-5 property space is highly desirable. A good understanding of laboratory equipment, automation, and associated software is desirable. You must be able to demonstrate strong experimental and problem-solving skills, excellent collaboration and communication skills (both written and oral), and an eagerness to learn. Demonstration of meeting timelines and excellent time management is favored. The ability to work in a team-based drug discovery/development environment is essential.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

• B.S. degree required; M.S in Cell Biology desirable or a closely related discipline
• 2 plus years of experience in a scientific laboratory role is desired.
• Understanding of bioanalysis utilizing LC-MS with special emphasis on the application of high throughput in vitro ADME sample analysis in a drug discovery setting as well as some experience with laboratory automation systems is preferable.


Why consider Novartis?

769 Million. That’s how many lives our products touched in 2020. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.
NIBR
Translational Medicine
USA
Cambridge, MA
Research & Development
Full Time
Regular
No
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315116BR

ADME Scientist, Assay Development

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