Experienced BS/MS level Scientist, Oncology Translational Research

Experienced BS/MS level Scientist, Oncology Translational Research
The successful candidate in this position will be playing a key role in evaluating new cancer drug candidates in pre-clinical and clinical development. Previous experience with oncology translational research projects would be beneficial.

Your Responsibilities:

Your responsibilities include, but not limited to:
•Evaluation of drugs and combinations based on responder hypotheses
•Perform initial assessment of potential biomarkers using assays such as ELISA, MSD, flow cytometry, gene expression profiling, and immune activation assays.
•Taking an active part in designing and developing new biological and chemical assays/screens to accelerate the current drug and biomarker discovery effort.
•Application of various genetic and chemical tools to dissect cancer and signal transduction pathways in different cancer models to help elucidate drug mechanisms of action as well as mechanisms that predict sensitivity and/or resistance.

What you'll bring to the role:
•Articulates key scientific questions, hypothesis generation, and project timeline planning
•Provide data analysis and propose designs for next experiments to supervisor
•Independently research and implement new lab techniques based on literature
•Independently write method and data summary reports
•Present and communicate data to supervisor, teams, and colleagues
•Demonstrate command of cancer biology and/or immunotherapy with ability to apply knowledge in discipline to complete work assignments
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Desirable Requirements:

Education (minimum/desirable):
•BS or MS (USA) in scientific discipline such as Biology, Biochemistry or Pharmacology with at least 5 years of experience in drug discovery or other related laboratory research

Experience/Professional requirement:
•Proficiency in mammalian cell culture and flow cytometry techniques is required.
•The ideal candidate will have additional experience in cell biology and molecular biology techniques. Familiarity with western blotting, compound efficacy profiling, viral based gene delivery, real-time qPCR, RNAi, or CRISPR technologies are highly desired.
•Familiarity with data analysis software and basic bioinformatics concepts are required.
Oncology NIBR
Cambridge, MA
Research & Development
Full Time