Scientific Associate for Skeletal Muscle Group, in vivo

Scientific Associate for Skeletal Muscle Group, in vivo
We seek a highly motivated and experienced Scientific Associate to join a laboratory in the Skeletal Muscle Group of the Musculoskeletal Disease Area (MSD) in Basel, Switzerland. You have a solid background in the field of in-vivo pharmacology and ex-vivo analysis. You will support muscular disease-related projects by testing candidate drugs in rodent models of muscular diseases, run already established models as well as develop new models and methods according to needs. In addition, you possess strong functional testing experience with rodents, cell culture, as well as solid experiences in biochemical, molecular biological and histology analysis.

Your main accountabilities:
1. Independently perform in-vivo experiments in a wide range of rodent models
• Handling, surgery and necropsy of rodents (e.g. compound administration, clinical monitoring, minipump implantation, cannulation, blood/organ sampling)
• Perform functional tests and surgeries in rodents (e.g. behaviour and locomotortests, cannulation, minipump implantation)
2. Perform ex-vivo analysis of tissues from rats and mice.
• Conduct biochemical, molecular biological and histology analysis
3. Demonstrate flexibility in adapting methods/skills according to evolving project priorities
4. Work collaboratively
5. Provide processed research data, evaluation and result interpretation
6. Optimize existing lab methods and develop new methods
7. General organization and maintenance of lab infrastructure, reporting and archiving of research data
Scientific degree in a relevant Life Science discipline (BS, MS, but no Ph.D.) or completed apprenticeship (biology), LTK1 accreditation or equivalent
• Fluent English is essential
• Communication skills in German and/or French would be an advantage
• 3 to 5 years of experience in a pharmacology lab working with rodents and conducting in-vivo experiments (handling and surgery, drug application, sampling, animal welfare regulations)
• Experience in biochemical, molecular biological, cell culture and histology techniques
• Flexible and prepared to develop a variety of in-vivo models and ex-vivo assays (e.g. qPCR, ELISA, western blot, enzymatic activities)
• Curiosity, initiative, commitment and good organizational skills
• Good communication skills; used to effectively work in a well-organized manner in a team environment
• Good computer skills in commonly used scientific software tools
Novartis Pharma AG
Research & Development
Full Time