Experienced BS/MS level Scientist, Oncology Translational Research

Experienced BS/MS level Scientist, Oncology Translational Research
We are seeking an experienced BS/MS level scientist to join our Oncology Translational Research team in Cambridge MA.

The successful candidate in this position will be playing a key role in evaluating new cancer drug candidates in pre-clinical and clinical development. Previous experience with oncology translational research projects would be beneficial.

Major responsibilities will include:
• Evaluation of drugs and combinations based on responder hypotheses
• Perform initial assessment of potential biomarkers using assays such as ELISA, MSD, flow cytometry, gene expression profiling, and immune activation assays.
• Taking an active part in designing and developing new biological and chemical assays/screens to accelerate the current drug and biomarker discovery effort.
• Application of various genetic and chemical tools to dissect cancer and signal transduction pathways in different cancer models to help elucidate drug mechanisms of action as well as mechanisms that predict sensitivity and/or resistance.
• Present and communicate data to supervisor, teams, and colleagues
• Maintaining a proficient and safe laboratory

Major activities:
• Articulates key scientific questions, hypothesis generation, and project timeline planning
• Provide data analysis and propose designs for next experiments to supervisor
• Independently research and implement new lab techniques based on literature
• Independently write method and data summary reports
• Maintain lab notebook with highest standards of data quality
• Present and communicate data to supervisor, teams, and colleagues
• Demonstrate command of cancer biology and/or immunotherapy with ability to apply knowledge in discipline to complete work assignments
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
• BS or MS (USA) in scientific discipline such as Biology, Biochemistry or Pharmacology with at least 5 years of experience in drug discovery or other related laboratory research
• Fluent English – Oral and written
• Must possess excellent oral and written communication and organizational skills, critical problem-solving abilities, and a commitment to science.
• Strong interpersonal skills.
• Proficiency in mammalian cell culture and flow cytometry techniques is required.
• The ideal candidate will have additional experience in cell biology and molecular biology techniques. Familiarity with western blotting, compound efficacy profiling, viral based gene delivery, real-time qPCR, RNAi, or CRISPR technologies are highly desired.
• Familiarity with data analysis software and basic bioinformatics concepts are required.
• Must be able to work independently, learn and become proficient in new techniques rapidly while also being an integral part of a highly dynamic team
Oncology NIBR
Cambridge, MA
Research & Development
Full Time